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Principal Scientist, Genomic Technologies, Human Genetics and Genomics Job Opening In Heidelberg – Now Hiring GSK

Principal Scientist, Genomic Technologies, Human Genetics and Genomics

    Germany Jobs Expertini Expertini Germany Jobs Heidelberg Life Scientists Principal Scientist, Genomic Technologies, Human Genetics And Genomics

Job description

We are seeking an innovative scientist to join our team.

The successful candidate will join the Genomic Technologies team, within the Human Genetics and Genomics (HGG) department at GSK.

In the Genomic Technologies group, we integrate deep and broad expertise in computational and statistical methods and techniques, to enable best-in-class analytical insight and interpretation of genetics and genomics data, to guide GSK’s drug discovery and development portfolio and pipeline decisions.

The successful candidate will join an existing Statistical Genetics team and will work on projects aligned to current areas of focus, including:

  • Discovery of new causal gene-phenotype links through analysis of large-scale individual level human genetic data.
  • Identification of causal genes, disease-relevant mechanisms and cell types, potential drug targets, candidate biomarkers, patient subgroups and disease subtypes, through integration of genetic association data across multiple ‘omic and phenotypic layers.
  • Predictive modelling of presence, direction and magnitude of causal gene-phenotype links, using genetic and ‘omic data, mechanistic annotation, inferred causal networks, and genome-scale perturbation data.

At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade.

Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people’s lives.

GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients’ needs and have the highest probability of success.

We’re uniting science, technology, and talent to get ahead of disease together.

Find out more:

In this role you will:

  • Evaluate, improve, test, and develop production implementations of best-in-class methods for analysis of genetic data, in collaboration with scientists in Data and Predictive Sciences, Biostatistics, or/and AI/ML teams.
  • Generate large-scale analysis outputs, and/or implement state-of-the-art tools for dynamically analysing, interpreting, and visualizing genetic and genomic data.
  • Collaborate with partners in applied and translational teams across HGG, in experimental Target Discovery, and in GSK disease area Research Units, to influence portfolio and pipeline decisions.
  • Stay informed about recent research in the field and consider its potential for application within GSK.
  • Contribute to a culture of innovation, quality, and willingness to learn and improve.

Why you?

Qualifications & Skills:

We are looking for a professional with these required skills to achieve our goals:

  • Advanced degree (PhD or equivalent) in a relevant scientific discipline.
  • Experience working with large scale biobank data, such as UK Biobank and All of Us.
  • Excellent programming skills in R or python, and application of techniques in reproducible research, literate programming, FAIR data principles, or software development.
  • Experience of evaluating, improving, testing, and/or developing methods for analysis and interpretation of large-scale genetics data.
  • Strong communication and team-working skills.

Preferred Qualifications & Skills:

If you have the following characteristics, it would be a plus:

  • Deep understanding of statistical genetics methodology.
  • Experience working in cloud-based Trusted Research Environments.
  • Experience with machine learning and/or advanced statistical methods.
  • Experience working in multidisciplinary teams on complex and impactful projects.
  • Experience with analysis of very large datasets using distributed or cloud computing technologies (e.g. SQL, PySpark, BigQuery, Docker, Nextflow).

This position may be based at a GSK R&D site in UK (Stevenage), in USA (Cambridge Tech Square, MA; or Upper Providence, PA), or in Germany (Heidelberg).

#HGG

Closing Date for Applications: 24th October 2025

Please take a copy of the Job Description, as this will not be available post closure of the advert.

When applying for this role, please use the ‘cover letter’ of the online application and your CV to describe how you meet the competencies for this role, as outlined in the job requirements above.

We encourage applicants to describe in their cover letter how their qualifications, skills and experience would make them outstanding contributors to the work of Genomic Technologies and of HGG.

The information that you have provided in your cover letter and CV will be used to assess your application.

Warum GSK?Wir vereinen Wissenschaft, Technologie und Talent, um Krankheiten gemeinsam voraus zu sein.

GSK ist ein globales Biopharma-Unternehmen mit der Ambition, Wissenschaft, Technologie und Talent zu vereinen, um Krankheiten gemeinsam voraus zu sein.

Wir haben uns zum Ziel gesetzt, bis zum Ende des Jahrzehnts die Gesundheit von 2,5 Milliarden Menschen positiv zu beeinflussen, als ein erfolgreiches, wachsendes Unternehmen, in dem sich unsere Mitarbeitenden entfalten können.

Wir behandeln und schützen vor Krankheiten mit Innovationen im Bereich Spezialmedizin und Impfstoffen.

Wir konzentrieren uns auf vier therapeutische Bereiche: Atemwegserkrankungen, Immunologie und Entzündungen; Onkologie; HIV; und Infektionskrankheiten – um die Gesundheit maßgeblich zu beeinflussen.

Menschen und Patient*innen auf der ganzen Welt zählen auf die Medikamente und Impfstoffe, die wir herstellen, daher sind wir bestrebt, ein Umfeld zu schaffen, in dem unsere Mitarbeitenden sich entfalten und sich auf das Wesentliche konzentrieren können.

Unsere Kultur, ambitioniert für Patient*innen zu sein, Verantwortung für Wirkungen zu übernehmen und das Richtige zu tun, ist die Grundlage dafür, wie wir gemeinsam für Patient*innen, Aktionär*innen und unsere Mitarbeitenden handeln.

GSK ist ein Arbeitgeber, der Chancengleichheit bietet.

Dies stellt sicher, dass alle qualifizierten Bewerber unabhängig von Rasse, Hautfarbe, Religion, Geschlecht (einschließlich Schwangerschaft, Geschlechtsidentität und sexueller Orientierung), Elternstatus, nationaler Herkunft, Alter, Behinderung, genetischen Informationen (einschließlich familiärer Krankengeschichte), Militärdienst oder einem anderen nach Bundes-, Landes- oder örtlichem Recht verbotenen Grund gleichberechtigt berücksichtigt werden.

Wir glauben an eine agile Arbeitskultur für alle unsere Rollen.

Wenn Flexibilität für Sie wichtig ist, ermutigen wir Sie, mit unserem Einstellungsteam zu besprechen, welche Möglichkeiten es gibt.

Sollten Sie Anpassungen an unserem Prozess benötigen, um Ihre Stärken und Fähigkeiten zu demonstrieren, kontaktieren Sie uns unter oder 0808 234 4391.

Die Hotline ist von Montag bis Freitag von 8.30 Uhr bis 12.00 Uhr erreichbar, an Feiertagen können diese Zeiten und Tage variieren.

Bitte beachten Sie, dass wir Ihnen bei Anfragen, die sich nicht auf Anpassungen beziehen, über diese Kanäle nicht weiterhelfen können.

Wir haben jedoch einen UK Recruitment FAQ-Leitfaden erstellt.

Klicken Sie auf den und scrollen Sie zum Abschnitt Karriere, wo Sie Antworten auf mehrere häufig gestellte Fragen finden.

Wichtiger Hinweis für Arbeitsvermittlungsunternehmen/Agenturen

GSK akzeptiert keine Empfehlungen von Arbeitsvermittlungsunternehmen und/oder Arbeitsvermittlungsagenturen in Bezug auf die auf dieser Website ausgeschriebenen Stellen.

Alle Arbeitsvermittlungsunternehmen/Agenturen müssen sich an die Abteilung für kommerzielle und allgemeine Beschaffung/Personalwesen von GSK wenden, um vorab eine schriftliche Genehmigung einzuholen, bevor sie Kandidaten an GSK verweisen.

Das Einholen einer vorherigen schriftlichen Genehmigung ist eine Voraussetzung für jede Vereinbarung (mündlich oder schriftlich) zwischen dem Arbeitsvermittlungsunternehmen/der Agentur und GSK.

Ohne eine solche schriftliche Genehmigung werden alle vom Arbeitsvermittlungsunternehmen/der Agentur durchgeführten Maßnahmen als ohne Zustimmung oder vertragliche Vereinbarung von GSK durchgeführt angesehen.

GSK haftet daher nicht für Gebühren, die aus solchen Maßnahmen oder aus Empfehlungen von Arbeitsvermittlungsunternehmen/Agenturen in Bezug auf die auf dieser Website ausgeschriebenen Stellen entstehen.

Bitte beachten Sie, dass GSK möglicherweise verpflichtet ist, Ausgaben, die GSK in Ihrem Namen tätigt, zu erfassen und zu melden, falls Sie ein US-lizenzierter Gesundheitsfachmann oder ein Gesundheitsfachmann gemäß den Gesetzen des Staates sind, der Ihre Lizenz ausstellt, und Ihnen ein Vorstellungsgespräch gewährt wird.

Diese Erfassung der anwendbaren Wertübertragungen ist notwendig, um die Einhaltung aller bundesstaatlichen und staatlichen US-Transparenzanforderungen durch GSK sicherzustellen.

Weitere Informationen finden Sie auf der Website der Centers for Medicare and Medicaid Services (CMS) unter

Required Skill Profession

Life Scientists


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Other Openings

Practice: Prepare answers to common interview questions and rehearse using the STAR method (Situation, Task, Action, Result) to showcase your skills and experiences.

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